| Spontaneous rhythmic contraction of separated heart muscle cells. | |
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MedLine Citation:
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PMID: 5416535 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Muscle cells that conitract spontaneously and rhythmically can be obtained from adult mouse myocardium. Contractions are observed immediately after homogenization in a solution that is ionically similar to intracellular fluid. Contraction frequency varies directly with temperature and decreases as a function of time after homogenization. At 16 degrees C rhythmic relaxation and contraction occur for about 20 minutes. Contractions are dependent on the presence of adenosine triphosphate in the homogenization medium. |
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Authors:
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S Bloom |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 167 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1970 Mar |
Date Detail:
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Created Date: 1970-04-14 Completed Date: 1970-04-14 Revised Date: 2011-12-07 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1727-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Triphosphate
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metabolism Animals Culture Media Culture Techniques* Heart / physiology Heart Ventricles Mice Muscle Contraction* Myocardium / cytology* |
| Chemical | |
Reg. No./Substance:
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0/Culture Media; 56-65-5/Adenosine Triphosphate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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