| Spontaneous remission of spasms in West syndrome--implications of viral infection. | |
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MedLine Citation:
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PMID: 11701282 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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On a database of the Japanese medical literature between 1970 and 2000, there were 29 patients with West syndrome showing spontaneous remission. In 25/29 (86%) of the patients, spontaneous remission was preceded by viral infections, among which exanthema subitum predominated. In 16/29 (55%), the spasms recurred a median of 2 months later. However, some of the remaining infants attained lasting remission of the spasms. This link between viral infections and spontaneous remission suggests immuno-inflammatory processes underlie West syndrome in certain patients. Better understanding of such mechanisms may lead to a new therapeutic approach to West syndrome. |
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Authors:
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H Hattori |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Brain & development Volume: 23 ISSN: 0387-7604 ISO Abbreviation: Brain Dev. Publication Date: 2001 Nov |
Date Detail:
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Created Date: 2001-11-09 Completed Date: 2002-02-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909235 Medline TA: Brain Dev Country: Netherlands |
Other Details:
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Languages: eng Pagination: 705-7 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Kyoto University School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. hhat2kuhp.kyoto-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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epidemiology,
virology Cytokines / immunology Humans Infant Neuroimmunomodulation Remission, Spontaneous Spasms, Infantile / epidemiology*, immunology, virology* Virus Diseases / epidemiology*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Cytokines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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