| Spontaneous remission of primary hyperparathyroidism: a case report and meta-analysis of the literature. | |
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MedLine Citation:
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PMID: 16284975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In a minority of patients, primary hyperparathyroidism spontaneously remits either by autoinfarction or by hemorrhage into or around the adenoma. We describe a case of autoparathyroidectomy occurring in a 63-year-old man 9 years after three parathyroid glands were removed during a total thyroidectomy. This case is compared with 50 previously reported cases of autoparathyriodectomy, and a meta-analysis is performed. METHODS: Case report, literature review, and meta-analysis were done using statistical software (SigmaStat 2.0, SPSS, Chicago). RESULTS: Fifty cases of autoparathyroidectomy were summarized according to the three etiologies. The greatest biochemical aberration was found in the acute intracapsular hemorrhage group, with [Ca(++)] falling from a mean 15.1 mg/dL to 8.9 mg/dL. The average drop in parathyroid hormone was 69% across all groups, comparing favorably to surgical resection. CONCLUSIONS: Autoparathyroidectomy is a rare but described outcome of unoperated primary hyperparathyroidism that may delay or supplant operative management. |
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Authors:
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Christopher T Wootten; Eric A Orzeck |
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Publication Detail:
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Type: Case Reports; Journal Article; Meta-Analysis; Review |
Journal Detail:
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Title: Head & neck Volume: 28 ISSN: 1043-3074 ISO Abbreviation: Head Neck Publication Date: 2006 Jan |
Date Detail:
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Created Date: 2005-12-21 Completed Date: 2006-07-06 Revised Date: 2006-10-05 |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 81-8 Citation Subset: IM |
Copyright Information:
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(c) 2005 Wiley Periodicals, Inc. Head Neck 27: XXX-XXX, 2005. |
Affiliation:
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Department of Otolaryngology, Vanderbilt University, 1215 21st Avenue South, Nashville, Tennessee 37232, USA. christopher.t.wootten@vanderbilt.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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complications*,
physiopathology,
radionuclide imaging Humans Hyperparathyroidism, Primary / etiology, physiopathology*, radionuclide imaging Male Middle Aged Parathyroid Neoplasms / complications*, physiopathology, radionuclide imaging Parathyroidectomy Remission, Spontaneous Thyroidectomy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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