| Spontaneous remission of functioning pituitary adenomas without hypopituitarism following infarctive apoplexy: two case reports. | |
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MedLine Citation:
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PMID: 15758567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Functioning pituitary adenomas may exhibit spontaneous remission after pituitary apoplexy usually in association with hypopituitarism. We report two patients who presented with sudden headache and double vision, showed a ring-enhanced sellar tumor on MRI, underwent transsphenoidal surgery that revealed a coagulation necrotic adenoma without massive hemorrhage, and showed normal pituitary function after the surgery. Definitive diagnoses were made based on immunohistochemistry of the necrotic cells. The findings were consistent with the presence of selective infarct of a GH adenoma and a prolactinoma that had led to remission of acromegaly and menstrual disturbance, respectively, without pituitary insufficiency. In contrast to hemorrhagic apoplexy, infarctive apoplexy tends to affect only the tumor and thus presents with mild symptoms and lack pituitary deficiencies. |
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Authors:
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Hiroshi Nishioka; Jo Haraoka; Tamotsu Miki |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Endocrine journal Volume: 52 ISSN: 0918-8959 ISO Abbreviation: Endocr. J. Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-03-10 Completed Date: 2005-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9313485 Medline TA: Endocr J Country: Japan |
Other Details:
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Languages: eng Pagination: 117-23 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Tokyo Medical University, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acromegaly
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etiology Adenoma / blood supply*, complications, diagnosis, surgery Adult Female Human Growth Hormone / secretion Humans Infarction / physiopathology* Magnetic Resonance Imaging Middle Aged Pituitary Apoplexy / physiopathology* Pituitary Neoplasms / blood supply*, complications, diagnosis, surgery Postoperative Period Prolactinoma / blood supply, physiopathology Remission, Spontaneous |
| Chemical | |
Reg. No./Substance:
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12629-01-5/Human Growth Hormone |
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