Document Detail


Spontaneous regression of a primary cerebral tumor following vasospasm caused by subarachnoid hemorrhage due to rupture of an intracranial aneurysm--case report.
MedLine Citation:
PMID:  15185757     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 40-year-old man demonstrated spontaneous regression of a malignant glioma following vasospasm caused by subarachnoid hemorrhage due to rupture of an intracranial aneurysm. The patient had been treated under a diagnosis of malignant glioma for 5 years. He presented with a ruptured aneurysm manifesting as subarachnoid hemorrhage. Single photon emission computed tomography with N-isopropyl-p-123I-iodoamphetamine and diffusion-weighted magnetic resonance (MR) imaging revealed severe flow reduction due to vasospasm in the bilateral temporoparietal cortical regions, including the tumor. MR imaging performed 5 months later showed marked tumor regression. The present case suggests that treatment targeting angiogenesis of malignant gliomas may be effective as a part of multimodality treatment.
Authors:
Yoji Yamashita; Toshihiro Kumabe; Hiroyuki Shimizu; Masayuki Ezura; Teiji Tominaga
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurologia medico-chirurgica     Volume:  44     ISSN:  0470-8105     ISO Abbreviation:  Neurol. Med. Chir. (Tokyo)     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-06-09     Completed Date:  2004-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400775     Medline TA:  Neurol Med Chir (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  187-90     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aneurysm, Ruptured / complications*
Brain Neoplasms / diagnosis,  etiology*,  physiopathology*
Cerebral Angiography
Glioma / diagnosis,  etiology*,  physiopathology*
Humans
Intracranial Aneurysm / complications*
Magnetic Resonance Imaging
Male
Remission, Spontaneous
Subarachnoid Hemorrhage / complications*
Tomography, Emission-Computed
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed
Vasospasm, Intracranial / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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