| Spontaneous regression of metastases from melanoma: review of the literature. | |
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MedLine Citation:
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PMID: 19633580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Regression of metastatic melanoma is a rare event, and review of the literature reveals a total of 76 reported cases since 1866. The proposed mechanisms include immunologic, endocrine, inflammatory and metastatic tumour nutritional factors. We conclude from this review that although the precise mechanisms remain unknown, some event must trigger the immune system to produce a stronger than normal response that results in regression of the melanoma metastases. Immunologic studies of patients with regression may disclose the underlying mechanisms and lead to new therapies of disseminated melanoma. |
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Authors:
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Louise Vennegaard Kalialis; Krzysztof T Drzewiecki; Helle Klyver |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Melanoma research Volume: 19 ISSN: 1473-5636 ISO Abbreviation: Melanoma Res. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-10 Completed Date: 2010-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9109623 Medline TA: Melanoma Res Country: England |
Other Details:
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Languages: eng Pagination: 275-82 Citation Subset: IM |
Affiliation:
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Department of Plastic Surgery and Burn Unit, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. drvennegaard@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Humans Lymphatic Metastasis Melanoma / immunology*, pathology, secondary* Neoplasm Regression, Spontaneous / immunology* Skin Neoplasms / immunology*, pathology, secondary* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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