Document Detail

Spontaneous regression of an anaplastic large cell lymphoma in the oral cavity: first reported case and review of the literature.
MedLine Citation:
PMID:  10705098     Owner:  NLM     Status:  MEDLINE    
Lymphomas account for 2-5% of all oral malignancies and are the third most common in this site. This case report appears to be the first in the world literature describing spontaneous regression in the oral cavity of a subset of non-Hodgkins lymphomas known as Ki-1 anaplastic large cell lymphomas (ALCL). Ki-1 ALCL account for 2-7% of all non-Hodgkins lymphomas and the clinical presentation is variable; they may arise de novo or in the setting of a separate primary lymphoma and commonly present in the extra-nodal location. Disease severity is also variable with waxing and waning lesions at one extreme which may spontaneously regress to bone marrow involvement in around 12% of cases. This case is especially interesting since the patient is a farmer, given the recent evidence that there may be a link between non-Hodgkins lymphoma and this occupation.
L Savarrio; J Gibson; D J Dunlop; N O'Rourke; E J Fitzsimons
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Oral oncology     Volume:  35     ISSN:  1368-8375     ISO Abbreviation:  Oral Oncol.     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-04-13     Completed Date:  2000-04-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9709118     Medline TA:  Oral Oncol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  609-13     Citation Subset:  IM    
Department of Oral Medicine, Glasgow Dental Hospital and School NHS Trust, 378 Sauchiehall Streert, Glasgow, UK.
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MeSH Terms
Agricultural Workers' Diseases / physiopathology*
Lymphoma, Large-Cell, Anaplastic / physiopathology*
Mouth Neoplasms / physiopathology*
Neoplasm Regression, Spontaneous*

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