Document Detail

Spontaneous pulmonary neoplasms in cynomolgus monkeys (Macaca fascicularis)--a report of two cases.
MedLine Citation:
PMID:  11665850     Owner:  NLM     Status:  MEDLINE    
The first lung tumour-bearing animal was a 7 years and 3 months old cynomolgus monkey. Microscopic examination revealed a neoplastic mass under the pleura that consisted of squamous islands with little keratinization, multifocal mineralization of the keratin, inflammatory cell and foreign body-type giant cell infiltration. It was classified as pulmonary squamous cell carcinoma. In a second cynomolgus monkey (2 years and 10 months old) a lung mass was observed at necropsy. Microscopically the tumour consisted of numerous islands of cartilage with glandular structures lined by a cuboidal epithelium between them. The neoplasm was classified as cartilaginous hamartoma.
J Kaspareit; S Friderichs-Gromoll; E Buse; R Korte; F Vogel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie     Volume:  53     ISSN:  0940-2993     ISO Abbreviation:  Exp. Toxicol. Pathol.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-10-22     Completed Date:  2002-02-28     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  9208920     Medline TA:  Exp Toxicol Pathol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  267-9     Citation Subset:  IM    
Covance Laboratories, Münster, Germany.
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MeSH Terms
Carcinoma, Squamous Cell / pathology,  veterinary*
Chondroma / pathology,  veterinary*
Fatal Outcome
Hamartoma / pathology,  veterinary*
Lung Neoplasms / pathology,  veterinary*
Macaca fascicularis*
Monkey Diseases / pathology*

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