Document Detail

Spontaneous preeclamptic toxemia of pregnancy in the patas monkey (Erythrocebus patas).
MedLine Citation:
PMID:  108469     Owner:  NLM     Status:  MEDLINE    
A disease characterized by edema, proteinuria, hypoproteinemia and hypertension was seen in late gestation in patas monkeys. The initial sign was edema of the perineum, ankles and lower trunk. The onset was abrupt, occurring 7 days or less prepartum. The affected animals were not depressed, and convulsions were not seen. In 6 of the 98 pregnancies during a 1-year period, symptoms of the disease were present. The highest incidence was manifested by primiparous animals with 3 of 36 pregnancies affected. Two of 38 second pregnancies and 1 of 24 third pregnancies were also affected. Five of the animals recovered spontaneously and were normal 14 days postpartum. Edema persisted for 30 days in one female. This animal continued to be hypertensive and had persistent mild proteinuria and hypoproteinemia. She was killed approximately 1 year postpartum due to severe renal disease. The spontaneous disease seen in patas monkeys resembled toxemia of pregnancy in humans more closely than the experimentally induced disease in other animals.
A E Palmer; W T London; D L Sly; J M Rice
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Laboratory animal science     Volume:  29     ISSN:  0023-6764     ISO Abbreviation:  Lab. Anim. Sci.     Publication Date:  1979 Feb 
Date Detail:
Created Date:  1979-07-25     Completed Date:  1979-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266503     Medline TA:  Lab Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  102-6     Citation Subset:  IM    
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MeSH Terms
Erythrocebus patas*
Monkey Diseases / blood*,  diagnosis
Pre-Eclampsia / blood,  diagnosis,  veterinary*
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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