Document Detail

Spontaneous pneumomediastinum and dermatomyositis may be a not so rare association: report of a case and review of the literature.
MedLine Citation:
PMID:  16622592     Owner:  NLM     Status:  MEDLINE    
One patient with dermatomyositis (DM) who developed spontaneous pneumomediastinum (SPnM) is described. A review of 15 previously reported cases shows that this is a complication of DM but not of polymyositis. It occurs in young patients with recent onset of disease characterized by cutaneous vasculopathy, and patients treated with immunosuppressive drugs have, in general, better outcomes. We suggest that the onset of SPnM in DM patients must alert to possible vasculitic activity and that immunosuppressive agents with progressive tapering of corticosteroids are part of the most reasonable approach in these cases.
Fabricio de Souza Neves; Fabricio de Souza Neves; Samuel Katsuyuki Shinjo; Jozélio Freire Carvalho; Maurício Levy-Neto; Cláudia Tereza Lobato Borges
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-04-19
Journal Detail:
Title:  Clinical rheumatology     Volume:  26     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-22     Completed Date:  2007-03-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  105-7     Citation Subset:  IM    
Division of Rheumatology, University of Sao Paulo, Sao Paulo, Brazil.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Dermatomyositis / complications*,  drug therapy
Immunosuppressive Agents / therapeutic use
Mediastinal Emphysema / drug therapy,  etiology*,  radiography
Middle Aged
Paraneoplastic Syndromes / complications*,  drug therapy
Skin Diseases, Vascular / complications*
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Immunosuppressive Agents
Erratum In:
Clin Rheumatol. 2007 Jan;26(1):138
Note: de Souza Neves, Fabricio [corrected to Neves, Fabricio de Souza]

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