| Spontaneous neoplastic lesions in aged Sprague-Dawley rats. | |
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MedLine Citation:
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PMID: 11381627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neoplastic lesions were observed in untreated aged Sprague Dawley (SD) rats throughout their lifespan starting at 5 weeks. Their mean survival times were 89 to 105 weeks of age. The total tumor incidences were 70 to 76.7% and 87 to 95.8% in males and females, respectively. The common neoplasmas were pituitary adenoma and adrenal pheochromocytoma in both sexes, testicular Leydig cell tumor in males and mammary gland tumors, thyroidal C-cell adenoma and uterine stromal polyp in females. |
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Authors:
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M Nakazawa; T Tawaratani; H Uchimoto; A Kawaminami; M Ueda; A Ueda; Y Shinoda; K Iwakura; K Kura; N Sumi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Experimental animals / Japanese Association for Laboratory Animal Science Volume: 50 ISSN: 1341-1357 ISO Abbreviation: Exp. Anim. Publication Date: 2001 Apr |
Date Detail:
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Created Date: 2001-05-30 Completed Date: 2001-10-04 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9604830 Medline TA: Exp Anim Country: Japan |
Other Details:
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Languages: eng Pagination: 99-103 Citation Subset: IM |
Affiliation:
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Research Laboratories, Nippon Shinyaku Co., Ltd., 14 Nishinosho-Monguchicho Kisshoin, Minami-ku, Kyoto 601-8550, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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epidemiology,
veterinary Adrenal Gland Neoplasms / epidemiology, veterinary Aging* Animals Female Leydig Cell Tumor / epidemiology, veterinary Male Mammary Neoplasms, Animal / epidemiology Neoplasms / epidemiology, veterinary* Pheochromocytoma / epidemiology, veterinary Pituitary Neoplasms / epidemiology, veterinary Polyps / epidemiology, veterinary Rats Rats, Sprague-Dawley Rodent Diseases / epidemiology* Testicular Neoplasms / epidemiology, veterinary Thyroid Neoplasms / epidemiology, veterinary Uterine Neoplasms / epidemiology, veterinary |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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