Document Detail

Spontaneous neonatal chylothorax treated with octreotide.
MedLine Citation:
PMID:  16487393     Owner:  NLM     Status:  MEDLINE    
Chylothorax is the most common cause of pleural effusion causing respiratory distress in the neonate. Cases unresponsive to conservative management usually require surgery. We report a case of spontaneous neonatal chylothorax where surgery was avoided with the compassionate trail of octreotide. The chylothorax resolved promptly with no observed side effects. After reviewing the literature reporting the use of octreotide in the neonatal period, we found that neonates with isolated spontaneous chylothorax might be viewed as a group different from those with major cardiac malformations. They are at a lower risk for adverse effect of octreotide and lower threshold for commencement of octreotide may benefit them most.
Sylvia L Y Siu; David S Y Lam
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  42     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-02-20     Completed Date:  2006-08-01     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  65-7     Citation Subset:  IM    
Department of Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Tuen Mun, New Territories, Hong Kong, China.
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MeSH Terms
Chylothorax / drug therapy*
Gastrointestinal Agents / administration & dosage,  therapeutic use*
Hong Kong
Infant, Newborn
Octreotide / administration & dosage,  therapeutic use*
Pleural Effusion
Treatment Outcome
Reg. No./Substance:
0/Gastrointestinal Agents; 83150-76-9/Octreotide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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