| Spontaneous and lectin-induced redistribution of cell surface receptors on embryonic chick neural retina cells. | |
| | |
MedLine Citation:
|
PMID: 1238408 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The mobility of plant lectin receptors in the plane of the membrane is examined for cells prepared from embryonic chick neural retinas by a variety of procedures. Cells liberated from the intact tissue by trypsin treatment followed by mechanical dissociation are able to redistribute their receptors into 'caps' both spontaneously and in the presence of a multivalent lectin. These cells, dispersed by trypsinization, upon repair in culture for a suitable period of time lose their ability to redistribute lectin receptors. Cells dispersed by mechanical means without prior trypsin treatment are unable to undergo 'cap' formation. In addition, cells within intact tissues are also unable to redistribute their lectin receptors into 'caps.' Based on these observations we propose that within solid tissues which have assumed their characteristic architecture, cell surfaces are immobilized, and that this phenomenon may be a critical parameter in determining the potential of a cell to undergo morphogenetic rearrangements. |
| | |
Authors:
|
J McDonough; J Lilien |
Related Documents
:
|
7543138 - Variant cell lines selected for alterations in the function of the hyaluronan receptor ... 16396498 - Analysis of total n-glycans in cell membrane fractions of cancer cells using a combinat... 22435758 - Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model st... 22764208 - Ultrasensitive clinical enumeration of rare cells ex vivo using a micro-hall detector. 6421058 - An enzyme-histochemical approach to the study of the human bone-marrow stroma. 17304218 - The asymmetric distribution of the essential histidine kinase pdhs indicates a differen... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Journal of cell science Volume: 19 ISSN: 0021-9533 ISO Abbreviation: J. Cell. Sci. Publication Date: 1975 Nov |
Date Detail:
|
Created Date: 1976-03-01 Completed Date: 1976-03-01 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0052457 Medline TA: J Cell Sci Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 357-68 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cell Membrane / drug effects*, ultrastructure Chick Embryo Fluoresceins Lectins / pharmacology* Microscopy, Fluorescence Receptors, Drug* Retina / drug effects*, innervation, ultrastructure Trypsin |
| Chemical | |
Reg. No./Substance:
|
0/Fluoresceins; 0/Lectins; 0/Receptors, Drug; EC 3.4.21.4/Trypsin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A rapid phytohemagglutinin induced alteration in lymphocyte potassium permeability.
Next Document: Determinants of experimental neurosis in cats.