| Spontaneous intra-hepatic haemorrhage in a patient with fever of unknown origin. | |
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MedLine Citation:
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PMID: 17664537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polyarteritis nodosa is a systemic necrotising vasculitis that affects the small- and medium-sized arteries. Multifocal aneurysmal formation in the renal, hepatic, and mesenteric vasculature is a hallmark of this condition, and spontaneous aneurysmal rupture may occur, resulting in life-threatening haemorrhage. We describe a 42-year-old man who initially presented with fever of unknown origin. A diagnosis could not be reached at that time despite extensive investigations. The fever subsided spontaneously after 8 weeks, and the patient remained well for 6 years until he was admitted again for evaluation of fever. During his hospital stay, he developed a spontaneous massive intra-hepatic haemorrhage resulting in hepatic rupture and a haemoperitoneum. The bleeding was controlled at emergency laparotomy. An abdominal angiography demonstrated multiple microaneurysms in the hepatic and mesenteric arterial vasculature. The clinical findings suggested polyarteritis nodosa, and the source of bleeding was probably a ruptured intra-hepatic artery aneurysm. |
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Authors:
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Vincent K S Leung; Clement Y W Lam; C C Chan; W L Ng; Tony K L Loke; I Sc Luk; T N Chau; Arthur H W Wu; W N Fong; S H Lam |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine Volume: 13 ISSN: 1024-2708 ISO Abbreviation: Hong Kong Med J Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-31 Completed Date: 2007-11-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9512509 Medline TA: Hong Kong Med J Country: China |
Other Details:
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Languages: eng Pagination: 319-22 Citation Subset: IM |
Affiliation:
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Department of Medicine and Geriatrics, United Christian Hospital, Kwun Tong, Hong Kong. vinju@netvigator.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aneurysm, Ruptured / complications* Fever of Unknown Origin / etiology* Hemorrhage / etiology* Hepatic Artery* Humans Liver Diseases / etiology* Male Polyarteritis Nodosa / complications* |
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