Document Detail

Spontaneous improvement in a patient with the hepatopulmonary syndrome assessed by serial exercise tests.
MedLine Citation:
PMID:  8066574     Owner:  NLM     Status:  MEDLINE    
A 37 year old patient with chronic active hepatitis progressing to cirrhosis presented with increasing breathlessness and was found to be hypoxic with finger clubbing. A progressive exercise study with measurement of oxygen saturation (SaO2) showed abnormally high ventilation and desaturation to 81% at 100 W. Serial studies over nearly two years showed, first, deterioration, then improvement with lower ventilation and higher saturation levels at all work loads. This could not be correlated with any change in treatment with azathioprine, prednisolone, or propranolol.
K B Saunders; S S Fernando; H R Dalton; A Joseph
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Thorax     Volume:  49     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-09-19     Completed Date:  1994-09-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  725-7     Citation Subset:  IM    
Department of Medicine, St George's Hospital and Medical School, London.
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MeSH Terms
Anoxia / drug therapy,  physiopathology*
Azathioprine / therapeutic use
Exercise Test / methods
Hepatitis, Chronic / physiopathology*
Liver Cirrhosis / drug therapy,  physiopathology*
Lung Diseases / drug therapy,  physiopathology*
Prednisolone / therapeutic use
Propranolol / therapeutic use
Remission, Spontaneous
Reg. No./Substance:
446-86-6/Azathioprine; 50-24-8/Prednisolone; 525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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