Document Detail

Spontaneous hepatic rupture: 13-year experience of a single center.
MedLine Citation:
PMID:  20555270     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Spontaneous hepatic rupture is a rare clinical event associated with various pathologies of the liver. Most series to date reported the incidence and characteristics of a single etiology. METHODS: Data were collected for all patients admitted with spontaneous hepatic rupture from 1995 to 2007. RESULTS: Ten patients met the study criteria. Hepatocellular adenoma was the cause of the rupture in six female patients, in their second to fourth decade. In the remaining patients, the ruptures were because of hepatocellular carcinoma in two, metastatic gastrointestinal stromal tumor in one, and HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count) in one. Nine out of 10 patients were treated surgically. CONCLUSION: Spontaneous hepatic rupture requires a high index of suspicion for a correct and timely diagnosis. Outcome is potentially grave and greatly depends on the underlying condition.
Daniel Maoz; Eran Sharon; Yakov Chen; Franklin Grief
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gastroenterology & hepatology     Volume:  22     ISSN:  1473-5687     ISO Abbreviation:  Eur J Gastroenterol Hepatol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-15     Completed Date:  2010-11-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000874     Medline TA:  Eur J Gastroenterol Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  997-1000     Citation Subset:  IM    
Department of Surgery A, Rabin Medical Center, Beilinson Campus, Petach Tikva, and Sackler Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Adenoma, Liver Cell / complications*
Carcinoma, Hepatocellular / complications
Gastrointestinal Stromal Tumors / complications*
HELLP Syndrome / physiopathology*
Liver Neoplasms / complications*
Middle Aged
Rupture, Spontaneous / diagnosis*,  epidemiology,  etiology*,  surgery
Treatment Outcome
Young Adult

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