| Spontaneous genomic fragility and cell cycle progression in lymphocytes of patients with cervical carcinoma. | |
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MedLine Citation:
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PMID: 8630975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty patients with invasive carcinoma of the cervix, along with 15 age-matched healthy females as controls, were studied to examine the frequency of spontaneous SCEs, chromosomal aberrations (CAs), and cell cycle progression in lymphocytes. The frequency of SCEs and TCAs was statistically significant in the patients over the control group. The correlation of SCEs and TCAs with the stage of cancer, age, and number of pregnancies was also made. The cell cycle of lymphocytes showed its prolongation in the patients, as is evident from the higher proportion of cells at M1 (metaphase of first cell division after 72 hours). |
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Authors:
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N Capalash; R C Sobti |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cancer genetics and cytogenetics Volume: 88 ISSN: 0165-4608 ISO Abbreviation: Cancer Genet. Cytogenet. Publication Date: 1996 May |
Date Detail:
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Created Date: 1996-07-01 Completed Date: 1996-07-01 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7909240 Medline TA: Cancer Genet Cytogenet Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 30-4 Citation Subset: IM |
Affiliation:
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Center for Biotechnology, Panjab University, Chandigarh, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cell Cycle* Cells, Cultured Chromosome Aberrations Chromosome Fragility* Female Humans Kinetics Lymphocytes / ultrastructure* Pregnancy Sister Chromatid Exchange Uterine Cervical Neoplasms / genetics*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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