| Spontaneous emergence of modularity in cellular networks. | |
| | |
MedLine Citation:
|
PMID: 17626003 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Modularity is known to be one of the most relevant characteristics of biological systems and appears to be present at multiple scales. Given its adaptive potential, it is often assumed to be the target of selective pressures. Under such interpretation, selection would be actively favouring the formation of modular structures, which would specialize in different functions. Here we show that, within the context of cellular networks, no such selection pressure is needed to obtain modularity. Instead, the intrinsic dynamics of network growth by duplication and diversification is able to generate it for free and explain the statistical features exhibited by small subgraphs. The implications for the evolution and evolvability of both biological and technological systems are discussed. |
| | |
Authors:
|
Ricard V Solé; Sergi Valverde |
Related Documents
:
|
6641263 - Computed tomography of pressure sores. 10455633 - Challenging the pressure sore paradigm. 15675213 - Comparison of disposable and reusable laryngeal mask airways in spontaneously ventilati... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of the Royal Society, Interface / the Royal Society Volume: 5 ISSN: 1742-5689 ISO Abbreviation: J R Soc Interface Publication Date: 2008 Jan |
Date Detail:
|
Created Date: 2007-11-22 Completed Date: 2008-03-04 Revised Date: 2013-06-06 |
Medline Journal Info:
|
Nlm Unique ID: 101217269 Medline TA: J R Soc Interface Country: England |
Other Details:
|
Languages: eng Pagination: 129-33 Citation Subset: IM |
Affiliation:
|
Complex Systems Lab, ICREA-UPF, Dr Aiguader 88, 08003 Barcelona, Spain. ricard.sole@upf.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biological Evolution* Cell Communication / physiology* Cell Physiological Phenomena* Models, Biological* |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The dynamic influence of genetic variation on the susceptibility of sheep to gastrointestinal nemato...
Next Document: Extremely fast prey capture in pipefish is powered by elastic recoil.