| Spontaneous course of Wegener's granulomatosis | |
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MedLine Citation:
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PMID: 3361797 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two cases of Wegener's granulomatosis are reported. During the 5 and 9 years course of the disease complete remissions and the disappearance of pulmonary opacities were found without specific treatment. Since 1970 cytotoxic drugs, e.g. cyclophosphamide, are frequently used for the treatment of Wegener's granulomatosis. The evaluation of the follow-up showed in these patients that in most cases the side-effects of the therapy, and not the primary disease, limited the life-expectancy. This especially applies for patients with mild forms of Wegener's granulomatosis, in which the initiation of a cytotoxic therapy should carefully be evaluated. |
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Authors:
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O Adam; H Wiesinger |
Publication Detail:
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Type: Case Reports; English Abstract; Journal Article |
Journal Detail:
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Title: Klinische Wochenschrift Volume: 66 ISSN: 0023-2173 ISO Abbreviation: Klin. Wochenschr. Publication Date: 1988 Mar |
Date Detail:
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Created Date: 1988-06-07 Completed Date: 1988-06-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985205R Medline TA: Klin Wochenschr Country: GERMANY, WEST |
Other Details:
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Languages: ger Pagination: 181-6 Citation Subset: IM |
Affiliation:
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Medizinische Poliklinik der Universität München. |
Vernacular Title:
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Spontanverläufe der Wegenerschen Granulomatose. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Cyclophosphamide / administration & dosage Drug Therapy, Combination Female Humans Lung / pathology Lung Diseases / pathology Maxillary Sinus / pathology Middle Aged Orbit / pathology Orbital Diseases / pathology Paranasal Sinus Diseases / pathology Prednisone / administration & dosage Pulmonary Artery / pathology Wegener Granulomatosis / pathology* |
| Chemical | |
Reg. No./Substance:
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50-18-0/Cyclophosphamide; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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