Document Detail

Spontaneous coronary artery dissection: case series with extended follow up.
MedLine Citation:
PMID:  21297205     Owner:  NLM     Status:  In-Data-Review    
Spontaneous coronary artery dissection (SCAD) is atherosclerotic or non-atherosclerotic in origin. Eosinophilic infiltrate is identified in coronary artery adventitia in non-atherosclerotic SCAD. We postulate that a systemic inflammatory state causes SCAD in younger women who do not have significant coronary artery disease risk factors. We report a case series of 13 patients presenting with SCAD from ages 26-48 with follow up from 1 month to 13 years. Most patients did not have conventional risk factors for coronary artery disease (CAD). Approximately 50% of the patients developed recurrent dissection within the first 2 weeks of an index event, but < 25% were symptomatic during follow up. All patients were alive at follow up. Systemic inflammatory state was observed in 80% of patients who developed early recurrent dissection. SCAD should be strongly suspected in younger women presenting with acute coronary syndrome without CAD risk factors. Coronary dissection may recur within first 2 weeks, but patients have good long-term survival without new episodes of dissection. Broad rheumatologic and connective tissue disease work-up should be considered in young females presenting with SCAD.
Pranav Kansara; Susan Graham
Related Documents :
18478795 - Aberrant ectatic internal carotid artery in the middle ear.
10442455 - Migraine with aura-like headache associated with moyamoya disease.
3628565 - Abnormal carotid arteries in the velocardiofacial syndrome: a report of three cases.
21609795 - National trends and regional variation of open and endovascular repair of thoracic and ...
15746745 - Assessment of minimally invasive direct coronary artery bypass grafting of the left int...
8181875 - Isolated left main coronary ostial stenosis: intraoperative transesophageal echocardiog...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  23     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  76-80     Citation Subset:  IM    
Department of Internal Medicine, The State University of New York at Buffalo, Buffalo, NY 14221, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of chronic Angiotensin converting enzyme inhibitor therapy on myocardial injury in patients u...
Next Document:  Percutaneous site-specific pharmacomechanical thrombolysis- thrombectomy system for bilateral acute ...