| Spontaneous circulating immune complex like material in Brown-Norway rats. Role of environmental factors. | |
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MedLine Citation:
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PMID: 6213776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Brown-Norway rats maintained under conventional housing conditions showed a significant increase in the C1q binding activity of serum and to a lesser extent of the Raji cell assay whereas no change was observed, in BN rats maintained under specific pathogen free (SPF) conditions. Glomerular IgG deposits were encountered among rats with circulating immune complexes (CIC). This suggests that microbiological environment is a major factor in the spontaneous appearance of CIC which could be of pathogenic significance. |
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Authors:
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B Bellon; P Verroust; C Mandet; P Druet |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of clinical & laboratory immunology Volume: 8 ISSN: 0141-2760 ISO Abbreviation: J Clin Lab Immunol Publication Date: 1982 Jun |
Date Detail:
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Created Date: 1982-10-29 Completed Date: 1982-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7808987 Medline TA: J Clin Lab Immunol Country: ITALY |
Other Details:
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Languages: eng Pagination: 133-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antigen-Antibody Complex* Complement Activating Enzymes / metabolism Complement C1q Environmental Exposure* Female Fluorescent Antibody Technique Germ-Free Life* Glomerulonephritis / chemically induced, immunology* Immunoglobulin G / analysis Male Rats Rats, Inbred BN Specific Pathogen-Free Organisms* |
| Chemical | |
Reg. No./Substance:
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0/Antigen-Antibody Complex; 0/Immunoglobulin G; 80295-33-6/Complement C1q; EC 3.-/Complement Activating Enzymes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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