| Spontaneous cerebrospinal fluid rhinorrhea: a clinical and anatomical study. | |
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MedLine Citation:
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PMID: 20717949 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES/HYPOTHESIS: Spontaneous nasal cerebrospinal fluid (CSF) fistula represents a rare clinical entity. The possible etiology and the localization of the rhinorrhea remain an ongoing clinical challenge. The purpose of this study was to evaluate the localization of spontaneous CSF fistula and to correlate it with anatomical studies. STUDY DESIGN: Retrospective clinical study, prospective anatomical study. METHODS: Twenty-nine patients with spontaneous CSF rhinorrhea were retrospectively studied, 10 males and 19 females. Ages ranged from 10 to 92 years (mean, 50 years). In addition, 48 human skulls from newborns to adults were examined for the postnatal development of the anterior and middle cranial fossa. RESULTS: In our study isolated cribriform plate defects were found in four patients. The lateral lamina of the ethmoid bone showed defects in three patients. In nine patients the bony defect could be found in the region of the fovea ethmoidalis. The bony defect between the extra- and intracranial space was found in the lateral recess of the sphenoid sinus in eight patients. Five patients had special sites (e.g., supraorbital recess and frontal recess). CONCLUSIONS: This study supports the theory that bony dehiscence in the lateral lamina of the ethmoid bone can be congenital and can also be spontaneously acquired later. The bony dehiscence in the lateral wall of the sphenoid sinus can only develop during pneumatization. |
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Authors:
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Miklós Tóth; Oxana Selivanova; Steven Schaefer; Wolf Mann |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Laryngoscope Volume: 120 ISSN: 1531-4995 ISO Abbreviation: Laryngoscope Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-09-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607378 Medline TA: Laryngoscope Country: United States |
Other Details:
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Languages: eng Pagination: 1724-9 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Johannes Gutenberg University Medical School, Mainz, Germany. toth@hno.klinik.uni-mainz.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Aged Aged, 80 and over Cerebrospinal Fluid Rhinorrhea / congenital, diagnosis*, pathology*, surgery Child Cranial Fossa, Anterior / pathology* Cranial Fossa, Middle / pathology* Ethmoid Bone / pathology, surgery Ethmoid Sinus / pathology, surgery Female Frontal Sinus / pathology Humans Infant, Newborn Magnetic Resonance Imaging Male Middle Aged Retrospective Studies Risk Factors Sphenoid Bone / pathology, surgery Sphenoid Sinus / pathology, surgery Tomography, X-Ray Computed Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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