| Spontaneous baroreflex sensitivity in young and older people during voluntary and electrically evoked isometric exercise. | |
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MedLine Citation:
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PMID: 12242198 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In young people, cardiovagal baroreflex sensitivity alters during isometric exercise. We investigated whether the reduced resting baroreflex sensitivity seen with increasing age is similarly altered during exercise. METHODS: Cardiovagal baroreflex sensitivity was examined in 8 young (age+/-SEM, 25+/-1.7 years) and 9 older (61+/-3.0 years) subjects, using sequence analysis during voluntary and electrically evoked isometric exercise (at 30% maximum voluntary strength) and during subsequent post-exercise circulatory occlusion. RESULTS: In all phases of both conditions, baroreflex sensitivity was significantly reduced in the older group compared with the young group. (Median (interquartile range), voluntary 7.0 (4.4) vs 3.6 (3.8) ms x mmHg(-1), post-exercise circulatory occlusion 9.0 (8.2) vs 4.6 (4.0) ms x mmHg(-1); electrically evoked 6.6 (10.6) vs 3.2 (3.6) ms x mmHg(-1), post-exercise circulatory occlusion 8.3 (7.7) vs 2.9 (2.2) ms x mmHg(-1), young vs older respectively; P<0.05.) There was a marked rightward shift (resetting) of the baroreflex during exercise with the exception of electrically evoked in the older group. CONCLUSION: Our data demonstrate that the reduction in baroreflex sensitivity in older people is maintained during exercise and during post-exercise circulatory occlusion. Resetting of the baroreflex in the older subjects during moderate voluntary isometric calf exercise is largely the result of central command. |
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Authors:
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Charlotte A Carrington; Michael J White |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Age and ageing Volume: 31 ISSN: 1468-2834 ISO Abbreviation: Age Ageing Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-20 Completed Date: 2008-02-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375655 Medline TA: Age Ageing Country: England |
Other Details:
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Languages: eng Pagination: 359-64 Citation Subset: IM |
Affiliation:
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School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. C.A.Carrington@bham.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aging / physiology* Baroreflex / physiology* Blood Pressure / physiology Electric Stimulation Exercise / physiology* Female Heart Rate / physiology Humans Male Middle Aged Muscle, Skeletal / innervation Neurons, Afferent / physiology Regression Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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