Document Detail

Spontaneous atrophic patches in extremely premature infants. Anetoderma of prematurity.
MedLine Citation:
PMID:  8651717     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Anetoderma, characterized clinically by macular depressions or outpouchings of skin, is associated with loss of dermal elastic tissue as noted on histopathologic findings. We report on 9 extremely premature infants who developed patches of anetoderma during their course in the neonatal intensive care unit. OBSERVATIONS: All 9 patients were born between the ages of 24 and 29 weeks of gestation and had numerous complications associated with prematurity. Eight of the 9 infants were noted to have developed anetoderma on the trunk and proximal extremities while in the neonatal intensive care unit. The locations of the lesions on the skin were not explained by previous trauma, although many areas corresponded with placement of monitoring leads or with adhesive for a monitoring device. Reduction or absence of elastic tissue supported the diagnosis of anetoderma in 4 of 5 biopsy specimens. CONCLUSION: We report a previously unrecognized type of anetoderma associated with extreme prematurity. The exact cause is uncertain, although reactions to cutaneous monitoring leads or adhesives is suspected.
T L Prizant; A W Lucky; I J Frieden; P S Burton; S M Suarez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  132     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-07-22     Completed Date:  1996-07-22     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  671-4     Citation Subset:  AIM; IM    
Department of Dermatology, University of Pittsburgh Medical School, Pa, USA.
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MeSH Terms
Elastic Tissue / pathology
Infant, Newborn
Infant, Premature, Diseases / pathology*
Skin / pathology*
Skin Diseases / pathology*
Comment In:
Arch Dermatol. 1997 Apr;133(4):526-7   [PMID:  9126031 ]
Arch Dermatol. 1997 Jun;133(6):789   [PMID:  9197841 ]

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