| Spontaneous activity in premature infants affects bone strength. | |
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MedLine Citation:
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PMID: 12478448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Determination of bone strength of lower extremities in very low birth weight (VLBW) premature infants with central nervous system pathology resulting in reduced unilateral spontaneous leg movements. STUDY DESIGN: Quantitative ultrasound (QUS) measurements of speed of sound (SOS) of the tibiae of both legs in three VLBW premature infants with brain insult and unilateral reduced spontaneous activity. Results were compared to QUS measurements of both legs in healthy premature infants. Measurements were performed by the same investigator who was blinded to the clinical course of the participants. RESULTS: Reduced spontaneous activity of one leg due to brain pathology resulted in decreased tibial SOS in the affected side. There was no difference in bone SOS between the legs of the healthy controls. CONCLUSION: Spontaneous movements (mainly antigravity flexion and extension) are important for bone structure and mineralization in VLBW premature infants. QUS may become an important diagnostic modality for the evaluation, treatment, and follow-up of bone strength and osteopenia in this unique population. |
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Authors:
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Alon Eliakim; Dan Nemet; Orit Friedland; Tzipora Dolfin; Rivka H Regev |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 22 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2002-12-12 Completed Date: 2003-04-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 650-2 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Meir Hospital, Kfar Saba, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Central Nervous System Diseases
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pathology,
physiopathology*,
ultrasonography Female Gestational Age Humans Infant, Newborn Infant, Premature / physiology* Infant, Premature, Diseases / pathology, physiopathology*, ultrasonography Infant, Very Low Birth Weight / physiology* Leg / pathology, physiopathology*, ultrasonography Male Motor Activity / physiology* Retrospective Studies Severity of Illness Index Tibia / pathology, physiopathology*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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