Document Detail

Spontaneous abdominal hematoma in a patient treated with clopidogrel therapy: a case report.
MedLine Citation:
PMID:  15626275     Owner:  NLM     Status:  MEDLINE    
Clopidogrel is a new antiplatelet agent. To date, no case of a spontaneous abdominal hematoma during clopidogrel therapy has been reported. We report a case of a 70-year-old woman who developed a spontaneous abdominal hematoma following clopidogrel treatment. The patient has been suffering from a progressive swelling in the abdominal wall for 1-2 weeks and noticed a purple discoloration of the skin over the swelled abdominal region the week before hospitalization. There was a palpable mass in the right upper quadrant of the abdomen and ecchymoses surrounding the umbilicus. At abdominal ultrasonography, the mass was found to be consistent with the hematoma. The hematoma was drained under local anesthesia. The patient was discharged with no complication. She was advised to submit herself to regular physical examinations. Although adverse reactions are generally rare, we suggest that physicians prescribing clopidogrel should be aware of the possibility of this adverse reaction.
Aytekin Guven; Gulizar Sokmen; Ertan Bulbuloglu; Cemal Tuncer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Italian heart journal : official journal of the Italian Federation of Cardiology     Volume:  5     ISSN:  1129-471X     ISO Abbreviation:  Ital Heart J     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-12-31     Completed Date:  2005-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909716     Medline TA:  Ital Heart J     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  774-6     Citation Subset:  IM    
Department of Cardiology, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaras, Turkey.
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MeSH Terms
Abdominal Wall / blood supply
Hematoma / chemically induced*,  diagnosis
Peritoneal Diseases / chemically induced*,  etiology
Platelet Aggregation Inhibitors / adverse effects*
Ticlopidine / adverse effects*,  analogs & derivatives*
Time Factors
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel

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