Document Detail


Spontaneous postpartum clearance of Plasmodium falciparum parasitemia in pregnant women, Benin.
MedLine Citation:
PMID:  21292897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The question of malaria in the postpartum period is controversial. Malaria was investigated during a randomized trial of intermittent preventive treatment in pregnancy in Benin. Women infected at delivery were tested for parasitemia in the early postpartum period; they had not received treatment unless they were symptomatic. Among the 35 of 1,346 infected women, parasitologic follow-up results could not be interpreted in 15 because they were treated for symptoms, 18 cleared parasitemia spontaneously within five days postpartum, and 2 had a strong decrease in parasitemia before being treated. Because the placenta is the privileged site for sequestration of parasites, it facilitates their persistence during pregnancy, and its elimination may rapidly induce their clearance.
Authors:
Julie Bottero; Valérie Briand; Carine Agbowai; Justin Doritchamou; Achille Massougbodji; Michel Cot
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  84     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-04     Completed Date:  2011-03-18     Revised Date:  2012-02-06    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  267-9     Citation Subset:  AIM; IM    
Affiliation:
Institut de Recherche pour le Développement, Unité Mixte de Recherche 216, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Benin
Female
Humans
Malaria, Falciparum / immunology*
Parasitemia / immunology*
Placenta / immunology,  parasitology
Plasmodium falciparum / immunology
Postpartum Period / immunology*
Pregnancy
Remission, Spontaneous
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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