Document Detail


Spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde inhibited by L-ascorbic acid.
MedLine Citation:
PMID:  6412697     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For the inhibition of spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde, L-ascorbic acid proved to be most suitable. The inhibition was not complete unless the molar concentration of ascorbic acid exceeded that of formaldehyde. T.l.c., potentiometric titration, n.m.r. spectroscopy and radiometric analysis were applied in the study of the inhibition process. Formaldehyde was reduced by L-ascorbic acid to ethylene glycol.
Authors:
L Trézl; I Rusznák; E Tyihák; T Szarvas; B Szende
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Biochemical journal     Volume:  214     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-10-21     Completed Date:  1983-10-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  289-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Ascorbic Acid / pharmacology*
Chemical Phenomena
Chemistry
Formaldehyde / metabolism*
Lysine / metabolism*
Magnetic Resonance Spectroscopy
Methylation
Chemical
Reg. No./Substance:
50-00-0/Formaldehyde; 50-81-7/Ascorbic Acid; 56-87-1/Lysine
Comments/Corrections

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