| Spontaneous intracranial hypotension without intracranial hypotension. | |
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MedLine Citation:
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PMID: 21119535 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 52-year-old man with a family history of multiple aneurysms presented with the gradual onset of generalized headaches and bilateral sixth nerve palsies. Following intravenous contrast, MRI revealed diffuse pachymeningeal enhancement consistent with spontaneous intracranial hypotension (SIH). Lack of any postural component to the headaches and repeatedly normal opening pressures on lumbar puncture delayed the diagnosis. A cerebrospinal fluid (CSF) leak was not found, but an epidural blood patch led to resolution of symptoms. Although the atypical features of nonorthostatic headache and normal CSF opening pressure have been documented in SIH, and failure to find the site of the leak is not unusual, this case illustrates a confluence of all these findings. An underlying disorder of connective tissue has been linked to SIH, and we propose that decreased meningeal compliance could account for a symptomatic low-volume state of CSF without a low opening pressure. |
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Authors:
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Tasneem Peeraully; Michael L Rosenberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Volume: 31 ISSN: 1536-5166 ISO Abbreviation: J Neuroophthalmol Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9431308 Medline TA: J Neuroophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 248-51 Citation Subset: IM |
Affiliation:
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New Jersey Neuroscience Institute, John F. Kennedy Medical Center (TP, MLR), Edison, New Jersey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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