Document Detail


Spontaneous 51Cr release by isolated rat hepatocytes: an indicator of membrane damage.
MedLine Citation:
PMID:  689706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Radiochromium uptake and release by isolated rat hepatocytes in suspension was monitored under continuous-labeling conditions. Cell protein remained unchanged during the absorption phase, whereas the release of 51Cr correlated well with the loss of cell viability and release of cytoplasmic protein. The results suggest that under equilibrium conditions, 51Cr release represents an efflux of label from damaged or dying preparations and not an elution of radioisotope from intact cells.
Authors:
R Zawydiwski; R Duncan
Related Documents :
7387176 - In vivo autoradiography and planimetry of epidermis in psoriatics under puva-therapy.
17071406 - Quantitative proteomics to study mitogen-activated protein kinases.
2202516 - Double labelling of cells with tritiated thymidine and bromodeoxyuridine reveals a circ...
25250126 - Comparative cytotoxic evaluation of free and sodium alginate nanoparticle-encapsulated ...
24389876 - A-single spermatogonia heterogeneity and cell cycles synchronize with rat seminiferous ...
14685696 - C-fos but not v-fos protein induces programmed cell death of v-myb-transformed monoblasts.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  In vitro     Volume:  14     ISSN:  0073-5655     ISO Abbreviation:  In Vitro     Publication Date:  1978 Aug 
Date Detail:
Created Date:  1978-12-02     Completed Date:  1978-12-02     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0063733     Medline TA:  In Vitro     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  707-14     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Ammonium Chloride / pharmacology
Cell Membrane / metabolism
Cell Survival*
Chromium Radioisotopes / diagnostic use*
Coloring Agents / diagnostic use
Liver / cytology*,  metabolism
Proteins / metabolism
Chemical
Reg. No./Substance:
0/Chromium Radioisotopes; 0/Coloring Agents; 0/Proteins; 12125-02-9/Ammonium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cartilage tissue differentiation from mesenchymal cells derived from mature muscle in tissue culture...
Next Document:  Identification of hydrogen peroxide as a photoproduct toxic to human cells in tissue-culture medium ...