| Spongy degeneration of the CNS in infancy. | |
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MedLine Citation:
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PMID: 6362628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied six cases of spongy degeneration of the CNS in infancy among Chinese. The main clinical features were cyclical vomiting and wailing, blindness, megalocephaly, convulsions, lethargy, and coma. Chief findings from light microscopic studies were spongiform change, moderate outfall of neurons, and marked astrocytosis, with formation of Alzheimer's cells type 2. Demyelination was only slight, if present. Electron microscopic studies revealed membrane-bound vacuoles, often containing membranous fragments or blisters and electron-dense granules. |
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Authors:
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Y Luo; K Huang |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 41 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-02-24 Completed Date: 1984-02-24 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 164-70 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asian Continental Ancestry Group Brain / ultrastructure Brain Diseases / pathology* Cerebral Cortex / pathology, ultrastructure Creutzfeldt-Jakob Syndrome / pathology Female Humans Infant Male |
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