Document Detail

Spongy cardiomyopathy in a neonate.
MedLine Citation:
PMID:  11558958     Owner:  NLM     Status:  MEDLINE    
Isolated noncompaction of ventricular myocardium is a rare cardiomyopathy, presumed to originate from a developmental abnormality in the evolution of the heart, and resulting in sponge-like myocardium. Isolated ventricular noncompaction can present with a variety of symptoms, but usually includes heart failure. The diagnosis is often made by echocardiography, which reveals a very distinct image of the myocardium, with many deep, confluent recesses and dense trabeculations. We encountered such findings in a moribund neonate presenting with cardiogenic shock with extremely low shortening fractions. After treatment with intravenous and oral cardiotonics, coupled with afterload reduction, we were able to optimize the balance between ventricular filling and myocardial contractility, resulting in markedly improved cardiac function as judged clinically, and as measured by echocardiography. As far as we know, this is one of the youngest patients yet reported to have a good recovery.
F J Halbertsma; L G van't Hek; O Daniëls
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiology in the young     Volume:  11     ISSN:  1047-9511     ISO Abbreviation:  Cardiol Young     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-09-17     Completed Date:  2002-01-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  458-60     Citation Subset:  IM    
Department of Paediatrics, Childrens Heart Centre, Nijmegen, The Netherlands.
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MeSH Terms
Cardiomyopathies / diagnosis,  etiology
Heart Defects, Congenital / complications,  diagnosis*
Infant, Newborn
Myocardium / pathology,  ultrastructure

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