Document Detail


Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature.
MedLine Citation:
PMID:  19370350     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study includes a case report and a literature review. The main objective of this study is to present a case of spondylodiscitis due to a fungal pathogen, Blastoschizomyces capitatus and to review the published literature on this emergent fungus in etiology of spondylodiscitis, and osteomyelitis. Osteoarticular involvement due to B. capitatus has been reported in six cases, and vertebral involvement has been seen in five of them. All of these cases had underlying malignancy. Infection is usually advanced at presentation. Case notes and online databases were reviewed. Organism was isolated from bone material in all of the cases and antibiotic treatment by antifungal agents cured the infection. We present another case of infectious spondylodiscitis due to B. capitaus, which is reported first in Turkey and tried to attract attendance to this emergent fungal pathogen as an etiologic agent of spine infections in cancer patients.
Authors:
Aygul Dogan Celik; Resat Ozaras; Serda Kantarcioglu; Ali Mert; Fehmi Tabak; Recep Ozturk
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-04-16
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  1437-160X     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-29     Completed Date:  2009-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1237-41     Citation Subset:  IM    
Affiliation:
Trakya University School of Medicine, Edirne, Turkey. adogancelik@yahoo.com.tr
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MeSH Terms
Descriptor/Qualifier:
Aged
Amphotericin B / pharmacology
Antifungal Agents / pharmacology,  therapeutic use
Dipodascus / drug effects,  isolation & purification,  pathogenicity*
Discitis / microbiology*
Fluconazole / pharmacology
Humans
Itraconazole / pharmacology
Ketoconazole / pharmacology
Lumbar Vertebrae / microbiology*,  pathology,  radiography,  surgery
Male
Microbial Sensitivity Tests
Naphthalenes / pharmacology
Opportunistic Infections / drug therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Naphthalenes; 1397-89-3/Amphotericin B; 65277-42-1/Ketoconazole; 84625-61-6/Itraconazole; 86386-73-4/Fluconazole; 91161-71-6/terbinafine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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