| Spondyloarthropathies in circumpolar populations of Chukotka (Eskimos and Chukchi): epidemiology and clinical characteristics. | |
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MedLine Citation:
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PMID: 7932421 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We sought to determine the prevalence of HLA-B27 and the prevalence and nature of spondyloarthropathies in the native residents of Eastern Chukotka, Siberia, Russia. METHODS: We conducted a cross sectional study with medical examination and interview of 464 of 640 (72.5%) native residents of 2 Eastern Chukotka settlements, Sireniki and Novo-Chaplino. RESULTS: Among them were 212 Eskimos, 98 Chukchi and 154 subjects of mixed race. There were 2 subjects (0.4%) with ankylosing spondylitis, 2 with Reiter's syndrome, 2 with undifferentiated spondyloarthropathy and 1 with late onset pauciarticular juvenile arthritis consistent with spondyloarthropathy. Four of the subjects were Eskimos, 2 were of mixed race, and 1 was Chukchi. We found a high percentage of HLA-B27 antigen in the population, 32% in the native population overall, and 40% among the Eskimos. CONCLUSION: Our data complement other studies of circumpolar populations and reinforce the reported high prevalence of spondyloarthropathy and HLA-B27 among those people. |
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Authors:
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S Erdesz; S V Shubin; B P Shoch; Krylov MYu; N M Mylov; N A Chekalina; L I Benevolenskaya |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of rheumatology Volume: 21 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 1994 Jun |
Date Detail:
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Created Date: 1994-10-25 Completed Date: 1994-10-25 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: CANADA |
Other Details:
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Languages: eng Pagination: 1101-4 Citation Subset: IM |
Affiliation:
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Department of Epidemiology and Genetics of Rheumatic Diseases, Institute of Rheumatology Russian Academy of Medical Sciences (RAMS), Moscow. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Child Continental Population Groups Female HLA-B27 Antigen / analysis Humans Inuits* Male Middle Aged Oceanic Ancestry Group* Prevalence Siberia / ethnology Spinal Diseases / epidemiology*, ethnology*, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/HLA-B27 Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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