Document Detail


Split hand/split foot deformity with focal dermal hypoplasia (Goltz syndrome).
MedLine Citation:
PMID:  21078256     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on a-6-months-old girl who manifested the phenotypic features of focal dermal hypoplasia. Significant limb deformities in connection with typical skin changes were documented. The family history had a high frequency of spontaneous abortions and male stillbirths. Male stillbirths are a landmark in favour of X-linked dominant pattern of inheritance. Despite the severe hand/foot deformities, the skull base and the tubular bones were sclerotic.
Authors:
Ali Al Kaissi; Hatem Safi; Maher Ben Ghachem; Franz Grill
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  20     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-16     Completed Date:  2011-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  770-2     Citation Subset:  IM    
Affiliation:
Department of Orthopaedics, Orthopaedic Hospital of Speising, Vienna, Austria. ali.alkaissi@osteologie.at
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MeSH Terms
Descriptor/Qualifier:
Female
Focal Dermal Hypoplasia / complications*,  diagnosis*,  genetics
Genetic Diseases, X-Linked / complications,  genetics,  radiography
Humans
Infant
Limb Deformities, Congenital / complications,  genetics,  radiography
Phenotype

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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