Document Detail

Splenic lymphoma with massive splenomegaly: Case report with review of literature.
MedLine Citation:
PMID:  25232555     Owner:  NLM     Status:  PubMed-not-MEDLINE    
As per strict criteria of Das Gupta et al, primary splenic lymphoma is very rare. Herein, we are reporting an unusual case of primary large cell splenic lymphoma of B lineage in a middle aged female presenting with massive splenomegaly (3.8 kg) and hypersplenism. After performing therapeutic splenectomy for hypersplenism, a precise diagnosis of diffuse large B cell lymphoma was made on histopathology and confirmed by immunohistochemistry. The patient responded well to standard (Cyclophosphamide, Hydroxydaunorubicin, Oncovin (vincristine), Prednisone or prednisolone) regimen last year and is now in full remission. The splenectomy thereby has prevented the potential grave complications related to hypersplenism and splenic rupture. Our aim behind highlighting the topic is to specify that emergency splenectomy followed by anticoagulation therapy is an effective plan of management to prevent untoward complications related to disease and treatment.
Sachin B Ingle; Chitra R Hinge Ingle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of clinical cases     Volume:  2     ISSN:  2307-8960     ISO Abbreviation:  World J Clin Cases     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-09-18     Completed Date:  2014-09-18     Revised Date:  2014-09-20    
Medline Journal Info:
Nlm Unique ID:  101618806     Medline TA:  World J Clin Cases     Country:  United States    
Other Details:
Languages:  eng     Pagination:  478-81     Citation Subset:  -    
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