| Splenic infarct as a diagnostic pitfall in radiology. | |
| | |
MedLine Citation:
|
PMID: 18688130 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Follow-up of colorectal carcinoma after therapy is based on symptoms, tumor markers, and imaging studies. Clinicians sometimes face diagnostic dilemmas because of unusual presentations on the imaging modalities coupled with rising serum markers. We report a case of colorectal carcinoma that presented with gastrointestinal symptoms 14 months after completion of treatment. Investigations showed rise in carcinoembryonic antigen (CEA). Suspecting disease recurrence, complete radioimaging workup was performed; the only abnormality detected was a smooth, hypodense area in the posterior third of the spleen on contrast-enhanced computed tomography abdomen. In view of the previous diagnosis of carcinoma colon, the symptoms reported by the patient, the elevated CEA, and the atypical CECT appearance, a diagnosis of splenic metastasis was made. The patient was subjected to splenectomy as a curative treatment. However, the histopathological report revealed it to be a splenic infarct. The present case reemphasizes the limitations of radiological studies in the follow-up of carcinoma colon. |
| | |
Authors:
|
Sanjeev C Joshi; Ishita Pant; Aditya N Shukla; M A Anshari |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of cancer research and therapeutics Volume: 4 ISSN: 1998-4138 ISO Abbreviation: - Publication Date: 2008 Apr-Jun |
Date Detail:
|
Created Date: 2008-08-08 Completed Date: 2008-11-13 Revised Date: 2009-01-12 |
Medline Journal Info:
|
Nlm Unique ID: 101249598 Medline TA: J Cancer Res Ther Country: India |
Other Details:
|
Languages: eng Pagination: 99-101 Citation Subset: IM |
Affiliation:
|
Department of Oncology, Palliative Care Unit, Radiology Advanced Medical and Dental Institute, Universiti Sains Malaysia, Pinang, Malaysia. scjoshi71@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma
/
diagnosis,
pathology,
surgery Aged Antimetabolites, Antineoplastic / therapeutic use Carcinoembryonic Antigen / blood Chemotherapy, Adjuvant Colectomy Colonic Neoplasms / diagnosis, pathology*, surgery Deoxycytidine / analogs & derivatives, therapeutic use Diagnosis, Differential Drug Administration Schedule Fluorouracil / analogs & derivatives, therapeutic use Follow-Up Studies Humans Lymphatic Metastasis / pathology Male Spleen / radiography* Splenectomy Splenic Infarction / radiography* Splenic Neoplasms / diagnosis, radiography*, secondary* Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Antimetabolites, Antineoplastic; 0/Carcinoembryonic Antigen; 154361-50-9/capecitabine; 51-21-8/Fluorouracil; 951-77-9/Deoxycytidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Primary melanoma of testis.
Next Document: rAAV vector-mediated gene therapy for experimental ischemic stroke.