Document Detail

Splenic abscess at Siriraj Hospital, Thailand.
MedLine Citation:
PMID:  2809452     Owner:  NLM     Status:  MEDLINE    
Splenic abscess is an unusual disease and may be presented either as a localized area of infection in the spleen or as a part of generalized sepsis. Population-based autopsy studies have established the incidence of splenic abscess at between 0.2-0.7 per cent. An eleven-year retrospective study of cases of splenic abscess treated at Siriraj hospital, a total of 9 cases, is presented. Pseudomonas pseudomallei is the most frequent causative agent, found in one-third of the cases, especially if the patient is thalassemic or a resident in the Northeastern part of the country. Thalassemia is also the leading predisposing condition of this malady with the incidence of 33 per cent. There are some differences in the presenting clinical features in Thai patients compared with those reported in the literature. Splenectomy was performed in all but one who died of leukemia preoperatively. The mortality rate of this disease in this series is 11 per cent and we recommend splenectomy under antibiotic coverage as soon as the diagnosis of splenic abscess has been confirmed.
P Watanapa; V Vathanophas
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  72     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-12-18     Completed Date:  1989-12-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  481-6     Citation Subset:  IM    
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MeSH Terms
Abscess / diagnosis,  epidemiology*,  microbiology
Hematologic Diseases / complications
Middle Aged
Pseudomonas Infections / diagnosis,  epidemiology*,  microbiology
Retrospective Studies
Splenic Diseases / diagnosis,  epidemiology*,  microbiology

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