Document Detail


Splenectomy in compound heterozygous hemoglobinopathies in Saudi Arabia.
MedLine Citation:
PMID:  2240476     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemoglobinopathies are a major public health problem in Saudi Arabia. We studied the effect of splenectomy in 16 Saudi Arabian children with compound hemoglobinopathies. Seven patients no longer require regular blood transfusions, and transfusion requirements were decreased by 30 to 60% in the other eight patients. Three patients whose heights and weights were below the 5th percentile before splenectomy reached the 25th percentile 1 year after the surgery. In spite of preoperative pneumococcal vaccination and the penicillin prophylaxis after the surgery, one patient died of Haemophilus influenzae Group B bacteremia, and three others had six episodes of pneumonia.
Authors:
T Sumer; I al-Mulhim; A Abumelha; M A Ahmed; S Khawaja
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of pediatric hematology/oncology     Volume:  12     ISSN:  0192-8562     ISO Abbreviation:  Am J Pediatr Hematol Oncol     Publication Date:  1990  
Date Detail:
Created Date:  1990-12-13     Completed Date:  1990-12-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7908071     Medline TA:  Am J Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  306-9     Citation Subset:  IM    
Affiliation:
Department of Pediatric Hematology/Oncology, University of Medicine and Dentistry of New Jersey, Camden.
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MeSH Terms
Descriptor/Qualifier:
Anemia, Sickle Cell / complications,  surgery
Child
Disease Susceptibility
Hemoglobinopathies / complications,  epidemiology,  genetics,  surgery*
Heterozygote
Humans
Infant
Retrospective Studies
Saudi Arabia / epidemiology
Splenectomy* / adverse effects
Thalassemia / complications,  surgery
Thrombocytosis / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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