Document Detail


Splenectomy for hypersplenism in malignant lymphomas.
MedLine Citation:
PMID:  7459599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Splenectomy has been performed in advanced malignant lymphomas in an effect to correct haematological cytopaenias in 41 patients since 1975. In both Hodgkin's disease and a variety of non-Hodgkin's lymphomas the operation has been associated with a high percentage of haematological correction (90 per cent overall). In many of these patients the haematological defect had prevented or led to the cessation of treatment and in those cases where chemotherapy was resumed after splenectomy worthwhile remission was achieved in 87.5 per cent of patients. There was no postoperative deaths and morbidity was considered acceptably low. We conclude that splenectomy is a valuable adjunct to treatment in advanced malignant lymphomas and should be considered at the first suggestion of splenic overactivity and reduced bone marrow reserves.
Authors:
P G Gill; R G Souter; P J Morris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  68     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1981 Jan 
Date Detail:
Created Date:  1981-04-21     Completed Date:  1981-04-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  29-33     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Female
Hematologic Diseases / etiology
Hodgkin Disease / mortality,  surgery
Humans
Hypersplenism / etiology,  surgery*
Lymphoma / complications,  mortality,  surgery*
Middle Aged
Postoperative Complications
Splenectomy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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