| Splanchnic non-hepatic hemodynamics and metabolism during liver transplantation. | |
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MedLine Citation:
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PMID: 18507110 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: The aim of this study is to compare the splanchnic non-hepatic hemodynamics and the metabolic changes during orthotopic liver transplantation between the conventional with bypass and the piggyback methods. METHODOLOGY: A prospective, consecutive series of 59 primary transplants were analyzed. Oxygen consumption, glucose, potassium, and lactate metabolism were quantitatively estimated from blood samples from the radial artery and portal vein, collected up to 120 minutes after graft reperfusion. Mean arterial pressure, portal venous pressure, portal venous blood flow, and splanchnic vascular resistance were also measured or calculated at postreperfusion collection times. RESULTS: There was a greater increase in portal venous blood flow (p=0.05) and lower splanchnic vascular resistance (p=0.04) in the piggyback group. Mean arterial pressure and portal venous pressure were similar for both groups. Oxygen, glucose and potassium consumption were higher in the piggyback group, but none of the metabolic parameters differed significantly between groups. CONCLUSIONS: In conclusion, the study detected a higher portal venous blood flow and a lower and splanchnic vascular resistance associated with the piggyback technique. After graft reperfusion, no difference in the splanchnic non-hepatic metabolic parameters was observed between the conventional with bypass and the piggyback methods of orthotopic liver transplantation. |
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Authors:
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Ana Olga Nagano Fernandes Mies; Paulo Celso Bosco Massarollo; Thomson Marques Palma; Sergio Mies |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 55 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2008 Jan-Feb |
Date Detail:
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Created Date: 2008-05-29 Completed Date: 2008-09-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 216-20 Citation Subset: IM |
Affiliation:
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5Liver Unit, Instituto Dante Pazzanese de Cardiologia, University of São Paulo Medical School, São Paulo, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Glucose / metabolism Humans Liver Transplantation / methods*, physiology* Male Middle Aged Oxygen Consumption Portal Vein / physiology Prospective Studies Regional Blood Flow Splanchnic Circulation / physiology* Vascular Resistance / physiology |
| Chemical | |
Reg. No./Substance:
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50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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