| Spirometric abnormalities in patients with allergic rhinitis: Indicator of an "asthma march"? | |
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MedLine Citation:
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PMID: 22186235 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Allergic rhinitis (AR) may precede and promote the onset of asthma. However, few studies addressed this issue mainly concerning bronchial physiological parameters. The aim of this study was to assess forced expiratory flow at 25-75% (FEF(25-75)), forced expiratory volume at 1 second (FEV(1)), and response to bronchodilation test in a large group of AR patients. METHODS: Sixteen hundred five adult AR patients were evaluated. Clinical examination, assessment of nasal obstruction perception by visual analog scale, spirometry, and bronchodilation test were performed in all patients. RESULTS: There were 8.4% of patients with abnormal FEV(1) values, 24.7% had impaired FEF(25-75), and 66.1% had reversibility with bronchodilation. A trend of spirometric impairment seems to exist in these patients. Age, gender, and duration of rhinitis may be risk factors for these findings. Different grades of bronchial impairment seem to exist. CONCLUSION: This study highlights the close link between upper and lower airways and suggests the possible existence of a progression from AR toward asthma, such as an "asthma march." Therefore, asthma should be suspected and carefully investigated in AR patients. |
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Authors:
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Giorgio Ciprandi; Alessio Signori; Maria Angela Tosca; Ignazio Cirillo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of rhinology & allergy Volume: 25 ISSN: 1945-8932 ISO Abbreviation: Am J Rhinol Allergy Publication Date: 2011 Sep-Oct |
Date Detail:
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Created Date: 2011-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101490775 Medline TA: Am J Rhinol Allergy Country: United States |
Other Details:
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Languages: eng Pagination: 181-5 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Azienda Ospedaliera Universitaria San Martino, Genoa, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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