Document Detail

Spirometric function improves in the morbidly obese after 1-year post-surgery.
MedLine Citation:
PMID:  20495965     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Obesity can negatively affect pulmonary function tests, with or without clinical symptoms, but the impact of bariatric weight loss is still debated. Aiming to document such profile in a consecutive homogeneous population, a prospective cohort study was undertaken.
METHODS: Sixty-one patients (100% females, age 40 +/- 8 years, BMI 49 +/- 5 kg/m(2) and without respiratory disease) were enrolled. Spirometric analysis was carried out to compare preoperative respiratory pattern with outcome after 6 and 12 months. Variables included vital capacity (VC), expiratory reserve volume (ERV), forced expiratory volume (1 s) (FEV1), FEV1/FVC ratio and maximum voluntary ventilation (MVV). Correlation of results with weight loss was examined.
RESULTS: The following initial variables exhibited significant difference when compared to the 12-month postoperative control: FVC (P = 0.0308), FEV1/FVC (P = 0.1998), MVV (P = 0.0004) and ERV (P = 0.2124). Recovery of FVC and FEV1/FVC occurred earlier by 6 months. The most seriously depressed preoperative finding was ERV, which even after 1 year still remained inadequate.
CONCLUSIONS: (1) Pulmonary limitations were diagnosed in approximately one third of the population. (2) Changes were demonstrated for FVC, FEV1/FVC, ERV and MVV. (3) FEV1 and FEV1/FVC were acceptable due to the absence of an obstructive pattern. (4) Two variables increased by 6 months (FEV1/FVC and ERV), whereas recovery for others was confirmed after 1 year. (5) The only exception was ERV which continued below the acceptable range.
Shirley Aparecida Fabris de Souza; Joel Faintuch; Ivan Cecconello
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obesity surgery     Volume:  20     ISSN:  1708-0428     ISO Abbreviation:  Obes Surg     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-30     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106714     Medline TA:  Obes Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1273-7     Citation Subset:  IM    
Department of Physical Therapy, Londrina State University, Londrina, Paraná, Brazil.
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MeSH Terms
Body Mass Index
Expiratory Reserve Volume
Forced Expiratory Volume
Gastric Bypass*
Maximal Voluntary Ventilation
Obesity, Morbid / physiopathology,  surgery*
Respiratory Function Tests*
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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