Document Detail


Spirocyclic systems derived from pyroglutamic acid.
MedLine Citation:
PMID:  21858317     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated.
Authors:
Andrew R Cowley; Thomas J Hill; Petr Kocis; Mark G Moloney; Robert D Stevenson; Amber L Thompson
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-22
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  -     ISSN:  1477-0539     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Chemistry, Chemistry Research Laboratory, The University of Oxford, Mansfield Road, Oxford, UKOX1 3TA.
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