Document Detail


Spinocerebellar degeneration.
MedLine Citation:
PMID:  2056261     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty cases with several forms of spinocerebellar degenerations were studied. The diagnosis was based on an appropriate clinical picture, radiological investigation and family history. There are multiple variants of spinocerebellar degeneration and classification of these diseases remains unsatisfactory and therefore controversial. We classified cases into three main groups. The numbers of cases in each of these groups were as follows: cerebellar group = 16 cases, cerebellar plus group = 9 cases, spinal group = 15 cases. The age, age of onset, mode of inheritance, clinical pictures and cerebrospinal fluid analysis of these cases were discussed. Results of various radiological investigations of these cases were reviewed. From our observations we can conclude that the morphologic changes seen in radiological investigations in our cases were more varied than the observed clinical syndromes. The cause of these syndromes remains unknown and there is no established treatment for spinocerebellar degeneration. We can only offer symptomatic treatment, physiotherapy and genetic counselling for this group of patients.
Authors:
K Phanthumchinda; A Srikiatkachorn
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  74     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-07-29     Completed Date:  1991-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  71-9     Citation Subset:  IM    
Affiliation:
Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Gait
Genes, Dominant
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Myelography
Pedigree
Pneumoencephalography
Spinocerebellar Degenerations / classification*,  diagnosis,  genetics
Tomography, X-Ray Computed

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