Document Detail


Spindle cell carcinoma of the parotid gland.
MedLine Citation:
PMID:  7561485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spindle cell carcinomas of the salivary gland are extremely rare, with only a few cases having been previously reported. We present a 55-year-old man with a rapidly enlarging mass in the left parotid gland. Despite radical surgery, the tumour recurred, and led to death 11 months later. Histopathologically, the tumour was composed of two components, a squamous cell carcinoma component and a spindle cell sarcomatoid component. A diagnosis of primary spindle cell carcinoma of the parotid gland was made. Immunohistochemical studies revealed keratin positivity and vimentin negativity in the squamous cell carcinoma component: the spindle cell sarcomatoid component was positive for vimentin and negative for keratin, but showed focal positivity for epithelial membrane antigen. The origin of the sarcomatoid component and the differential diagnosis from malignant mixed tumours are discussed.
Authors:
T Ishibashi; H Hojo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  109     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-10-30     Completed Date:  1995-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  683-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Otolaryngology, Kanto Teishin Hospital, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / diagnosis*,  pathology
Humans
Immunohistochemistry
Keratins / analysis
Male
Middle Aged
Parotid Neoplasms / diagnosis*,  pathology
Chemical
Reg. No./Substance:
68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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