Document Detail

Spindle cell carcinoma of the larynx.
MedLine Citation:
PMID:  15121229     Owner:  NLM     Status:  MEDLINE    
Four rare cases of spindle cell carcinoma of the larynx are reported and the histo-pathological and immuno-histochemical findings are described. The spindle cell carcinoma involved the right vocal cord of an 88-year-old and an 86-year-old male patients and the anterior commissure of a 76-year-old and a 68-year-old male patients. Two patients underwent total laryngectomy, one patient extirpation under laryngomicrosurgery and one radiation therapy. All were well controlled thereafter and there was no recurrence. Surgery seemed to be the most satisfactory therapeutic approach and radiation therapy was effective in a patient with relatively small tumor. The histo-pathological and immuno-histochemical analysis in one patient revealed a sarcoma-like component of the carcinoma and the findings suggested that this was the result of a metaplastic change in the mesenchyme without inflammatory changes.
Hiroshi Miyahara; Yoshihiro Tsuruta; Katsunari Yane; Yoshinobu Ogawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Auris, nasus, larynx     Volume:  31     ISSN:  0385-8146     ISO Abbreviation:  Auris Nasus Larynx     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-05-03     Completed Date:  2005-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708170     Medline TA:  Auris Nasus Larynx     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Nara Medical University, 800 Shijo-cho, Kashihara 637-8522, Nara, Japan.
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MeSH Terms
Aged, 80 and over
Carcinoma / complications,  pathology*,  surgery
Hoarseness / etiology
Laryngeal Neoplasms / complications,  pathology*,  surgery
Radiotherapy, Computer-Assisted
Treatment Outcome
Vocal Cords / pathology

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