Document Detail

Spindle cell epulis in an 8-month-old child: a histologic variant of congenital granular cell epulis?
MedLine Citation:
PMID:  22421995     Owner:  NLM     Status:  MEDLINE    
A case of an epulis in an 8-month-old boy is reported. The tumor was localized on the mandibular alveolar ridge and, according to the parents, was a recurrence of a congenital tumor excised when the boy was 2 months old. Microscopically, it was composed of many spindled or ovoid cells with vesicular nuclei and non-granular eosinophilic cytoplasm, and covered by acanthotic parakeratinized squamous epithelium with broad rete pegs. Immunohistochemically, the spindled and ovoid cells were intensely positive for vimentin and neuron-specific enolase, and negative for S-100 protein. The final diagnosis was spindle cell epulis. The possible correlation of this lesion with congenital granular cell epulis is discussed.
Andreas-Christoforos Prigkos; Michail D Nikolakis; Vasileios F Kyriakopoulos; Konstantinos I Tosios
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-03-16
Journal Detail:
Title:  Head and neck pathology     Volume:  6     ISSN:  1936-0568     ISO Abbreviation:  Head Neck Pathol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-19     Completed Date:  2013-05-16     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101304010     Medline TA:  Head Neck Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  467-70     Citation Subset:  IM    
Department of Oral Pathology, Dental School, University of Athens, 2 Thivon street, 11527 Athens, Greece.
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MeSH Terms
Gingival Neoplasms / congenital*,  pathology*,  surgery
Granular Cell Tumor / congenital*,  pathology,  surgery
Neoplasm Recurrence, Local / metabolism,  pathology,  surgery

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