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Spindle Cell Epulis in an 8-Month-Old Child: A Histologic Variant of Congenital Granular Cell Epulis?
MedLine Citation:
PMID:  22421995     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A case of an epulis in an 8-month-old boy is reported. The tumor was localized on the mandibular alveolar ridge and, according to the parents, was a recurrence of a congenital tumor excised when the boy was 2 months old. Microscopically, it was composed of many spindled or ovoid cells with vesicular nuclei and non-granular eosinophilic cytoplasm, and covered by acanthotic parakeratinized squamous epithelium with broad rete pegs. Immunohistochemically, the spindled and ovoid cells were intensely positive for vimentin and neuron-specific enolase, and negative for S-100 protein. The final diagnosis was spindle cell epulis. The possible correlation of this lesion with congenital granular cell epulis is discussed.
Authors:
Andreas-Christoforos Prigkos; Michail D Nikolakis; Vasileios F Kyriakopoulos; Konstantinos I Tosios
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-16
Journal Detail:
Title:  Head and neck pathology     Volume:  -     ISSN:  1936-0568     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101304010     Medline TA:  Head Neck Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
, 6-7 Poseidonos street, Athens, 17561, Greece.
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