Document Detail

Spinal myoclonus in subacute combined degeneration caused by nitrous oxide intoxication.
MedLine Citation:
PMID:  17685135     Owner:  NLM     Status:  MEDLINE    
A 26-year-old patient developed ascending weakness and paresthesias. Megaloblastic anemia and mildly reduced serum vitamin B12 (B12) concentration were noted. Myoclonus-like muscular contractions appeared over four extremities and in the trunk. She admitted inhaling nitrous oxide (N2O) as a euphoriant repeatedly at party. Following parenteral B12 administration, her neurological deficit promptly resolved. This case demonstrated the abuse of N2OI is an important cause of subacute combined degeneration (SCD) of the spinal cord. To our knowledge, this is the first report of involuntary movements in a patient with N2O intoxication. Although the mechanism remains unknown, involuntary movements similar to myoclonus should be considered as one of the extraordinary neurological manifestations of N2O intoxication.
Mei-Shian Wu; Yaw-Don Hsu; Jiann-Chyun Lin; Shih-Cheng Chen; Jiunn-Tay Lee
Related Documents :
16532335 - Direct emergence of the dorsospinal artery from the aorta and spinal cord blood supply....
644395 - Arachnoiditis ossificans. report of a case.
9950385 - Vocal cord dysfunction mimicking a severe asthma attack.
9792985 - Micturitional disturbances due to labial adhesion.
24745795 - Urologic stenting-induced trauma: a comprehensive review and case series.
25073215 - Primitive pulmonary "malignant epithelioid hemangioendothelioma" versus epithelioid ang...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurologica Taiwanica     Volume:  16     ISSN:  1028-768X     ISO Abbreviation:  Acta Neurol Taiwan     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-08-09     Completed Date:  2007-08-23     Revised Date:  2008-05-28    
Medline Journal Info:
Nlm Unique ID:  9815355     Medline TA:  Acta Neurol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  102-5     Citation Subset:  IM    
Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Magnetic Resonance Imaging
Myoclonus / chemically induced*
Nitrous Oxide / poisoning*
Spinal Cord Diseases / chemically induced*
Subacute Combined Degeneration / chemically induced*
Vitamin B 12 / therapeutic use
Reg. No./Substance:
10024-97-2/Nitrous Oxide; 68-19-9/Vitamin B 12

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Familial hyperhomocysteinemia-related cerebral venous sinus thrombosis and pulmonary embolism: a cas...
Next Document:  Sleep-related eating disorder in a 29 year-old man: a case report with diagnostic polysomnographic f...