| Spinal factors affecting pulmonary function in patients with scoliosis. | |
| | |
MedLine Citation:
|
PMID: 21529450 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Objective To investigate pulmonary function impairment and the spinal factors that may determine pulmonary function in patients with scoliosis. Methods Seventy-eight patients with idiopathic scoliosis or congenital scoliosis and 78 age- and gender-matched healthy subjects were enrolled in this study. The radiographic parameters of spinal deformity were obtained from patients with scoliosis. Both two groups received pulmonary function tests. Results Patients with scoliosis demonstrated a restrictive pattern of pulmonary function impairment with a proportional decrease in both forced expiratory volume in one second and forced vital capacity. Total lung capacity and functional residual capacity were reduced. Carbon monoxide diffusion capacity was decreased, while diffusion coefficient remained normal or slightly higher. Airway resistance and conductance were not affected. In addition, airway resistance and residual volume were found abnormal in patients with congenital scoliosis. Multiple linear regression analysis showed that three spinal factors including involved thoracic vertebrae, vertical height from C7 to S1, and Cobb angle were independently responsible for 40%-51% of total variances of forced vital capacity, forced expiratory volume in one second, total lung capacity, and functional residual capacity .Conclusions Patients with scoliosis have restrictive ventilation defects. More thoracic vertebrae involvement, lower vertical height, and larger Cobb angle are associated with severer impairment of lung volume. |
| | |
Authors:
|
Hao Ran; Wu Zhi-Hong; Han Jiang-Na; Meng Shu-Zhen; Zhu Yuan-Jue; Yu Bin; Wang Yi-Peng; Qiu Gui-Xing |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae Volume: 33 ISSN: 1000-503X ISO Abbreviation: Zhongguo Yi Xue Ke Xue Yuan Xue Bao Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-05-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8006230 Medline TA: Zhongguo Yi Xue Ke Xue Yuan Xue Bao Country: China |
Other Details:
|
Languages: eng Pagination: 194-9 Citation Subset: IM |
Affiliation:
|
Department of Respiratory Medicine,PUMC Hospital, CAMS and PUMC,Beijing 100730, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of Drag-reducing Polymers on Microcirculation of Normal Rat Hindlimb Skeletal Muscle.
Next Document: Detection of Genetic Variations of Regulator of G-protein Signaling 2 in Hypertensives by Sequencing...